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We’re dedicating this blog to answering all of your most urgent weight loss injections questions. From how The 1:1 Diet is the perfect complementary solution, to common side effects, our top nutritionist, Mark Gilbert, is here to set the record straight once and for all.
Do weight loss injections work?
Yes. There are currently 2 main types of weight loss injections available on prescription: Wegovy® (semaglutide) and Zepbound® (Tirzepatide). These are administered once a week, usually by injection, and they both work primarily by making you feel fuller and less hungry.
Faced with a decreasing appetite, The 1:1 Diet can help. With a variety of both light and nutritionally complete meal solutions, once you’ve found the right plan for you, our Diet will help you maintain your weight loss, while getting the goodness your body needs to thrive. And while GLP-1s can suppress appetite, they don’t deliver the habit-building or the long-term guidance needed to maintain results after the injections stop. That’s where we come in.
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Do you gain weight after weight loss injections?
It used to be thought that losing too much weight, too quickly, meant that you’d be at greater risk of regaining weight, but this is no longer thought to be the case. In fact, research, including the DROPLET study, carried out by University of Oxford obesity experts on The 1:1 Diet, along with other studies, demonstrates that rapid initial weight loss predicts better results in the long term. However, it should be noted that (in a key study on Wegovy) people who came off the weight loss injections without any additional support, regained substantial weight rapidly.
That’s why we’d always recommend pairing rapid initial weight loss with comprehensive nutritional support, as it will improve long-term outcomes. And that’s where The 1:1 Diet comes in. Each of our meal replacements is around 200 calories, packed with protein, and 25 vitamins and minerals.
Plus, you’ll have the ongoing support of habit-building. After all, studies have shown that if you don’t make the necessary dietary and behavioural changes, you will most likely regain the weight you’ve lost.
What are the side effects of weight loss injections?
Like many medications, weight loss injections also may have mild initial symptoms while your body adjusts to the changes. The most common side effects can include nausea, vomiting, bloating, constipation, and diarrhoea. In rare cases, side effects can also include gallbladder and kidney problems, pancreas inflammation and depression. As always, if you experience any of these while on the weight loss drugs, make sure you reach out to your GP.
Are weight loss injections only for people with Type 2 diabetes?
Many of the weight loss injections were initially developed to help those with Type 2 diabetes. This is because they work by lowering blood sugar and increasing insulin production, helping to prevent your liver from releasing too much sugar. More recently, some of these medications have also been licensed for weight management.
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How long do the weight-loss drugs take to work and why?
These drugs must be started on a very low dosage, because if they are started at the full dosage, then they can cause unacceptable levels of nausea, stomach upset and vomiting. The dosage is then gradually increased, over several weeks, to eventually achieve the desired effect.
To put this in perspective, on The 1:1 Diet, multiple studies show that subjects lose, on average, at least 1 ½ stone in the first 8 weeks. Using Mounjaro (semaglutide used for weight loss), it takes 20 weeks to lose this amount of weight.*
Want to achieve sustainable weight loss while getting the nutrition your body deserves? Then make sure you reach out to your Consultant. They’ll be more than happy to discuss your options with The 1:1 Diet and explore how you can achieve the best results in the healthiest way.
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*John P. H. Wilding, Rachel L. Batterham, Melanie Davies, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. Diabetes, Obesity & Metabolism. 24(8), 2022. 1553-64.
The 1:1 Diet does not sell or supply GLP-1 medications. This is for general information only and is not medical advice. Always speak to your doctor before starting a weight loss programme, especially if you are using medication such as weight loss injections.